Dr. Robinson is a Research Assistant Professor in the Department of Otolaryngology-Head and Neck Surgery. He conducted his Batchelor of Science Degree in biochemistry at the University of Bath, Avon, England. He received his M.S. and Ph.D. degrees in the biochemistry and molecular biology of steroid hormone regulated gene expression in breast cancer within the Ben May Institute for Cancer Research at the University of Chicago. He conducted post-doctoral research at Northwestern University in otology and olfaction and joined the faculty in 2000. He is currently shifting his focus from the olfactory system to hearing research within the department. Current studies involve prevention of cell death following aminoglycoside treatment in rodents and following noise exposure.
"Inhibition of apoptosis as a means to mitigate hearing loss in mice" (Funded by the E.R. Capita Foundation)
|Freshly exposed gerbil cochlea (AC-apical turn of cochlea)|
with ossicles (O) still in place and stapedal artery (SA)
as a useful landmark for orientation.
The efficacy of the antibiotic minocycline as a therapeutic agent for amelioration of hearing loss in gerbils treated with the ototoxic aminoglycoside, neomycin was investigated. Minocycline is multifaceted in that it exhibits anti-inflammatory, antibiotic and anti-apoptotic properties in several neural and non-neural tissues.
Mid modiolar section of gerbil cochlea demonstrating
cochlear turns (bars) with sprial ganglion (SG) regions
used to quantify spiral ganglion neurons (arrows).